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AMPL
AMPL, an acronym for "A Mathematical Programming Language", is an algebraic modeling language for describing and solving high-complexity problems for large-scale mathematical computation (i.e. large-scale optimization and scheduling-type problems). AMPL supports dozens of solvers, both open source and commercial, including CBC, CPLEX, FortMP, Gurobi, MINOS, IPOPT, SNOPT and KNITRO. Problems are passed to solvers as nl files. AMPL is used by more than a hundred corporate clients. It is also used by government agencies and academic institutions. [Wikipage]
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Gretl
gretl is an open-source statistical package, mainly for econometrics. The name is an acronym for Gnu Regression, Econometrics and Time-series Library. It has a graphical user interface and can be used together with X-12-ARIMA, TRAMO/SEATS, R, Octave, and Ox. It is written in C, uses GTK as widget toolkit for creating its GUI, and uses gnuplot for generating graphs. As a complement to the GUI it also has a command line interface. gretl can output models as LaTeX files. [Wikipage]